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Dr. Suling Liu is currently a professor at Fudan University Cancer Hospital and Institutes of Biomedical Sciences. Dr. Liu's research has focused on characterization and regulation mechanisms of normal and malignant breast stem cells. Evidence from this research is of obvious significance for the development of new diagnosis tools and innovative treatments for breast cancer. After getting PhD from Ohio State University in Dec 2003, her research interest on breast carcinogenesis took her to focus on cancer therapy to find novel treatments to cancer by targeting the cancer stem cells. In the past, she has been studying the role of Hedgehog pathway, Notch pathway, Bmi-1, BRCA1, tumor microenvironment and microRNAs in the regulation of human mammary stem cell self-renewal and differentiation by developing both the in vitro and in vivo systems for breast stem cell research. In recent years, as a corresponding author, Dr. Liu has been published in Nature Cell Biology、Advanced Science、Nature Communications、Science Advances、Clinical Cancer Res.、Plos Biology and other famous SCI Journals at a total over 25 research articles (total over 79 publications which has been cited over 10000 times). Dr. Liu’s contributions to the fields of breast stem cells have been recognized by a number of international awards including Leading Innovative Talents in the Science and Technology of China for Young and Middle Aged People (2020), Leading Medical Talents in Shanghai (2019), Young Cancer Research Investigator in China (2018), USCACA‐NFCR Scholarship Award (2014), Susan G Komen postdoctoral fellowship (2005-2008), AACR Merck Scholar-in-training award (2006), AACR Susan G Komen Scholar-in-training award (2010). In 2012, Dr. Liu received the Chinese Thousand Youth Talents Plan. In 2013, Dr. Liu received the NSFC Outstanding Young Investigator Award. As an independent PI, Dr. Liu has been supported by many research grants from both USA and China.
Research Focus:
1. The
Regulation and drug resistance of heterogenous breast cancer stem cells；
2. The
origin of breast cancer stem cells；
3. The
interaction of breast cancer stem cells and tumor microenvironment；
4. The
immune-regulation of breast cancer stem cells；
5. The
development of potential therapeutic approaches and drugs to target breast
cancer stem cells.
