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2010年毕业于中国科学院研究生院,获理学博士学位。2010年至2015年在美国西南医学中心从事博士后研究工作。2016年至今,任职于复旦大学附属肿瘤医院肿瘤研究所,主要从事DNA损伤修复、细胞损伤与免疫应激等方面研究,研究成果以通讯作者或第一作者发表在Molecular Cancer,Frontiers in microbiology, Cell
Reports等杂志。
研究领域:
1.DNA损伤修复分子机制研究;
2.细胞损伤与免疫应激;
3.CDK7调控及肿瘤靶向治疗;
4.重离子治癌机理研究。
研究团队:
代表性论著:
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Wei, Y#.; Li, C#.; Bian, H.;
Qian, W.; Jin, K.; Xu, T.; Guo, X*.; Lu, X*.; Su, F*. Targeting CDK7
suppresses super enhancer-linked inflammatory genes and alleviates CAR T
cell-induced cytokine release syndrome. Molecular cancer. 2021 Jan 4; 20(1):5.
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Xu, T#.; Shen, C#.; Wei, Y.; Hu,
C.; Wang, Y.; Xiang, J.; Sun, G. H.; Su, F*.; Wang, Q*.; Lu, X*. Human
papillomavirus (HPV) in Chinese oropharyngeal squamous cell carcinoma (OPSCC):
A strong predilection for the tonsil. Cancer medicine. 2020 Sep; 9(18):6556-6564.
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Li, C.; Lu, L.; Qi, Z.; Zhu, Y.; Su, F*.; Zhao,
P*.; Dong, H*. Transcriptome and miRNome Analysis Provide New Insight Into Host
Lipid Accumulation, Innate Immunity, and Viral Persistence in Hepatitis C Virus
Infection in vitro. Frontiers in microbiology. 2020 Sep 30; 11:535673.
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Su, F.; Mukherjee, S.; Yang, Y.; Mori, E.; Bhattacharya,
S.; Kobayashi, J.; Yannone, S. M.; Chen, D. J.; Asaithamby, A. Nonenzymatic
role for WRN in preserving nascent DNA strands after replication stress. Cell
reports. 2014 Nov 20; 9(4):1387-401.
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Su, F.; Smilenov, L. B.; Ludwig, T.; Zhou, L.; Zhu, J.;
Zhou, G.; Hall, E. J. Hemizygosity for Atm and Brca1 influence the balance
between cell transformation and apoptosis. Radiation oncology. 2010 Feb 22; 5:15.
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