金伟 研究员 研究员，博士生导师 E-mail: jinwei7207@163.com

      2006年9月回国来到复旦大学附属肿瘤医院乳腺癌研究所工作。作为课题负责人，主持了多项国家自然科学基金，以及教育部新世纪优秀人才基金、上海市浦江人才计划基金、上海市卫生计生系统优秀学科带头人基金、上海市教委科研创新项目、教育部留学回国人员启动基金、上海市自然科学基金等多项省部级基金；已在国内外期刊杂志上发表论文40余篇，论文发表于Theranostics、J Biol Chem、Mol Cell Biol、Breast Cancer Res Treat、Biochem Pharmacol 等学术杂志；担任国家自然科学基金等项目的通讯评议专家；担任8家SCI杂志审稿人，还担任中国抗癌协会抗癌药物专业委员会委员、上海市抗癌协会乳腺癌专业委员等社会学术职务。

研究领域：

　　主要从事乳腺癌转移相关的研究，目前主要研究方向包括：
　　1.脂质代谢与乳腺癌转移； 

　　2.线粒体相关基因在乳腺癌转移中的作用;

      3.转录因子与乳腺癌发生发展的研究。

研究团队：

　　小组成员共7位：孙荷芬（研究助理）、李良东（博士研究生）、李璇（博士研究生）、徐宝金（博士研究生）、顾筱莉（博士研究生）。

代表性论著：

1. Liu Y^#, Sun H, Li X, Liu Q, Zhao Y, Li L, Xu B, Hou Y^*, Jin W^*. Identification of a Three-RNA Binding Proteins (RBPs) Signature Predicting Prognosis for Breast Cancer. Front Oncol. 2021 Jul 12; 11:663556.

2. Li X^#, Sun H^#, Liu Q, Liu Y, Hou Y^*, Jin W^*. A pharmacophore-based classification better predicts the outcomes of HER2-negative breast cancer patients receiving the anthracycline- and/or taxane-based neoadjuvant chemotherapy. Cancer Med. 2021 Jul; 10(13):4658-4674.

3. Fu W^#, Sun H, Zhao Y, Chen M, Yang X, Liu Y, Jin W^*. BCAP31 drives TNBC development by modulating ligand-independent EGFR trafficking and spontaneous EGFR phosphorylation. Theranostics. 2019 Aug 21;9(22):6468-6484.

4. Liu QQ^#, Sun HF^#, Yang XL, Chen MT, Liu Y, Zhao Y, Zhao YY, Jin W^*. Survival following radiotherapy in young women with localized early-stage breast cancer according to molecular subtypes. Cancer Med. 2019 Jun; 8(6):2840-2857.

5. Huang S^#, Chi Y^#, Qin Y^#, Wang Z, Xiu B, Su Y, Guo R, Guo L, Sun H, Zeng C, Zhou S, Hu X, Liu S, Shao Z, Wu Z, Wei J^*, Wu J^*. CAPG enhances breast cancer metastasis by competing with PRMT5 to modulate STC-1 transcription. Theranostics, 2018; 8(9): 2549-2564.

6. Chen M^#, Zhao Y, Yang X, Zhao Y, Liu Q, Liu Y, Hou Y, Sun H^*, Jin W^*. NSDHL promotes triple-negative breast cancer metastasis through the TGFβ signaling pathway and cholesterol biosynthesis. Breast Cancer Res Treat. 2021 Jun;187(2):349-362.

7. Zhao Y^#, Sun HF^#, Chen MT, Gao SP, Li LD, Jiang HL, Jin W^*. Clinicopathological characteristics and survival outcomes in Paget disease: a SEER population-based study. Cancer Med, 2018 Jun; 7(6):2307-2318.

8. Chen MT^#, Sun HF^#, Zhao Y, Fu WY, Yang LP, Gao SP, Li LD, Jiang HL, Jin W^*. Comparison of patterns and prognosis among distant metastatic breast cancer patients by age groups: a SEER population-based analysis. Sci Rep, 2017 Aug 23; 7(1):9254.

9. Gao SP^#, Sun HF^#, Li LD, Fu WY, Jin W*. UHRF1 promotes breast cancer progression by suppressing KLF17 expression by hypermethylating its promoter. Am J Cancer Res, 2017 Jul 1; 7(7):1554-1565.

10. Gao SP^#, Sun HF^#, Fu WY, Li LD, Zhao Y, Chen MT, Jin W^*. High expression of COX5B is associated with poor prognosis in breast cancer. Future Oncol, 2017 Aug;13(19):1711-1719.